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 Rated 4.9 By 12,600+ Customers

Nativesisters™- Retinol Spicule Cream

Nativesisters™- Retinol Spicule Cream

check_circle Micro Spicules Deliver Collagen Deeper Than Any Cream Can Alone

check_circle Proprietary Colletinol™ Capsules — Real Collagen + Retinal In Every Drop

check_circle Clinically Certified (KFDA Approved) For Wrinkles, Elasticity & Radiance

Micro spicules are ultra-fine, naturally derived particles from hydrolyzed sea sponge. When applied to skin they create thousands of tiny microchannels, similar to professional microneedling, that allow collagen and retinal to penetrate far deeper than any regular cream can. You may feel a mild tingling sensation during application, which is completely normal and simply means the spicules are working. The formula includes panthenol and multiple soothing agents specifically to keep the experience gentle and comfortable. No redness, no irritation, no downtime, just deeper delivery and better results.

(1) Remove the clear cap from the ampoule vial. (2) Insert the syringe needle through the rubber stopper. (3) Tilt the vial upside down and gently pull the syringe plunger to extract the serum. (4) Slide the syringe tip directly onto your skin and gently massage in upward, lifting motions until the golden threads completely dissolve. (5) When finished, leave the syringe inserted in the vial to maintain freshness between uses.

Simply break open one of the collagen and retinal capsules directly into the gel base and mix them together with your fingertip or a spatula before applying to clean skin. One of the most loved features of this product is that the capsule-to-gel ratio is fully customizable. If your skin is more sensitive or you are new to retinal, start with less capsule and more gel. As your skin builds tolerance, increase the capsule amount for more intensive results. You can also target specific areas, using more capsule on deeper lines around the forehead, neck, and mouth while using a lighter application on more delicate areas.

This is one of the most thoughtfully formulated retinal products available for sensitive skin. The inclusion of panthenol, 8 types of hyaluronic acid, and niacinamide creates a deeply soothing and hydrating environment that significantly reduces the irritation that traditional retinol products are known for. The customizable capsule ratio also means you are in complete control of how much retinal your skin receives. We recommend starting with a lower capsule ratio 2 to 3 nights per week and gradually increasing frequency as your skin adjusts. The vast majority of customers with sensitive skin report no irritation whatsoever.

Yes, and this is actually where the NativeSisters™ Deep Collagen Retinol Capsule Cream truly sets itself apart from every other cream on the market. Deep wrinkles and severe sagging are caused by a significant loss of structural collagen in the deeper layers of the skin, and that is precisely what this formula is engineered to address.

Water, Butylene Glycol, Glycerin, Methylpropanediol, 1,2-Hexanediol, Niacinamide, Silk Water, Carbomer, Tromethamine, PPG-13-Decyltetradeceth-24, Propanediol, Hydrolyzed Collagen, Adenosine, Chondrus Crispus Powder, Agar, Hydroxyethyl-cellulose, Disodium EDTA, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Synthetic Fluorphlogopite, Betaine, Panthenol, Glycine Soja (Soybean) Peptide, Titanium Dioxide (CI 77891), Iron Oxides (Cl 77491), Mica (CI 77019), Gellan Gum, Magnesium Ascorbyl Phosphate, Centella Asiatica Extract, Houttuynia Cordata Extract, Tin Oxide, Ethylhexylglycerin, Squalane, Benzyl Glycol, Lecithin, Hydrolyzed Glycos-aminoglycans, Sodium Hyaluronate, Caprylyl Glycol, Hydrogenated Lecithin, Ca-prylic/Capric Triglyceride, sh-Polypeptide-121, Sodium Palmitoyl Sarcosinate, To-copherol, Sodium Hyaluronate Crosspolymer, Acetyl Glutamine, Caffeoyl Heapep-tide-65, Hydrolyzed Hyaluronic Acid, Heptasodium Hexacarboxymethyl Dipep-tide-12, Bacillus/Folic Acid/Soybean Ferment Extract, Gold, Sodium Phosphate, Collagen, Hydroxypropyltrimonium Hyaluronate, Dextran, Benzoic Acid, Sodium Benzoate, Hydrolyzed Elastin, Myristoyl Pentapeptide-17, Myristoyl Pentapeptide-4, sh-Polypeptide-123, Palmitoyl Pentapeptide-5, Acetyl Tetrapeptide-3, Trifolium Pratense (Clover) Flower Extract, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Hyaluronic Acid, Palmitoyl Tetrapeptide-7, sh-Decapeptide-7.

Current Shipping Times

USA: 6-12 Business Days

Canada: 7-12 Business Days

UK & EU: 10-15 Business Days

UAE: ~20 Days

South Africa: 20-25 Days

Australia/New Zealand: 15-20 Business Days

Other International Orders: 15-25 Business Days

90 Day Money Back Guarantee!

If you're not completely satisfied with your product for any reason, simply return it within 90 days of the arrival date for a full refund, no questions asked. Our hassle-free return policy ensures that you can try our product with confidence, knowing that you can get your money back if it doesn't meet your expectations.

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They Lifted. They Transformed.

    All Corners Of Your Face

    Designed to be placed on any spot where Wrinkles, Sagging, Lines, or Indents are present!

    Forehead

    Eye Area

    Cheeks

    Mid Face

    Chin & Jawline

    General Indentations

    What To Expect

    Before

    After

     
     

    Results You Can Feel!

    96%

    Reported visibly plumper, more hydrated skin within the first 2 weeks of use

    93%

    Noticed a visible reduction in fine lines and wrinkles by the end of month 2

    90%

    Reported a more even, brighter skin tone and reduced appearance of dark spots

    Based On A Post Purchase Customer Survey

    We Do It Best.

    See how our Retinol Spicule Cream stacks up. Real ingredients, real results, and real confidence you can feel from the inside out.

      Others
    Instant Tightening Effect
    Lifts Mid-Face Volume
    Reduces Deep Wrinkles
    Restores Facial Contour
    No Needles Required
    19 Clinical Studies

    Trustpilot Reviews

    Excellent 4.9 / 5

    • "Skin firming and wrinkle results I can actually see."

      I noticed visible skin firming and tightening within a few weeks. It worked wonders on my wrinkles and crow's feet. The fact that I can feel the micro spicules working gives me confidence that the ingredients are actually penetrating, not just sitting on top. One of a kind retinol cream. Nothing else comes close.

      Sumitra V.

    • "Some improvements within two weeks and another must have."

      I started seeing improvements in my skin texture and hydration within just two weeks. My skin feels noticeably plumper and the fine lines around my mouth look softer. The capsule system is genius, I love being able to customize how much I use based on what my skin needs that night. This is permanently in my routine.

      Colleen R.

    • "Absolutely amazing, my skin looks and feels incredible."

      I cannot say enough good things about this cream. My skin has never looked or felt this good. The glow is real, the firmness is real, and I wake up every morning looking more rested and radiant than the night before. I've tried luxury creams at triple the price that didn't do half of what this does.

      Christi M.

    • "I replaced my entire anti-aging routine with this one product."

      I used to spend over $200 a month on separate retinol, collagen serum, peptides, and hyaluronic acid. This cream has everything in one and it performs better than any of them did individually. Skin is firmer, brighter, and more hydrated than it's been in years. The customizable capsule ratio is a genius touch. I'm genuinely never going back.

      Angela T.

    • "The tingling is proof it's working, and it absolutely is."

      I was a little nervous about the spicule tingling at first but it's very gentle, just enough to know something is happening. And it definitely is. By week 3 my skin texture was noticeably smoother. By week 6 my husband asked if I'd gotten a facial. I hadn't. I'd just been using this cream every night. That says everything.

      Lindsey P.